Genk’s fourth title -- and first since 2011 -- came with the last round of the season to be completed on Sunday.
Genk were ahead at Anderlecht after 11 minutes through Bryan Heynen but Anderlecht's Yannick Bolasie, on loan from Everton, headed home at the far post to equalise in the 65th minute.
Despite having to face seven shots on target, Australia's Danny Vukovic only conceded the one goal.
A nervy Genk, coached by Philippe Clement, held out for the last 25 minutes to secure the crucial point which proved enough as defending champions Bruges went down at Standard.
Standard's Romanian international Razvan Marin, who is joining Ajax Amsterdam next season, converted a second half penalty and added a spectacular second in his last home game.
