In a new documentary titled Made In Senegal, Mane peeled back the layers of his past and detailed the life-changing day his father died.
The news, delivered by a cousin, left a seven-year-old Mane stunned and in disbelief in the middle of a Bambali field.
"He had this kind of sickness for weeks,” Mane told the Guardian.
"We brought him some traditional medicine and it kept him calm for three or four months.
"The sickness came back but this time the medicine didn’t work and because there was no hospital in Bambali they had to take him to the next village to see if they could save his life. But it was not the case.
"When he died, it had a big impact on me and the rest of my family. I said to myself: ‘Now I have to do my best to help my mother.’
"That’s a hard thing to deal with when you are so young.”
His father's passing set the wheels in motion to bring about change in the Sedhiou province and, two decades on, the Liverpool star has done just that.
With a school built and a hospital on its way, significant strides have been taken to help reduce the presence of poverty in the region, where some 70 per cent of families struggle, according to the World Bank.
"I remember my sister was also born at home because there is no hospital in our village," he added.
"It was a really, really sad situation for everyone. I wanted to build one to give people hope.”
Mane's charitable nature has since seen the Senegalese government receive £40,000 (A$80,400) to help reduce the spread of the coronavirus, a pandemic responsible for the Premier League's postponement.
And while there appears to be no certainty surrounding the resumption of the 2019-20 season, the 27-year-old remains eager to continue his quest to keep hope alive.
"You should be in good health before you go to work, so let’s finish the hospital," Mane said.
"When you see these kind of people and the offerings in front of the house, you think: ‘Wow, I have to work even harder for them'."
