Sevilla, Leverkusen, Basel through to Europa quarters

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Sevilla beat Roma 2-0 in the round of 16 on to stay in the hunt for a record sixth UEFA Europa League title, as Wolverhampton, Bayer Leverkusen and Basel also qualified for the quarter-finals.

Full-back Sergio Reguilon gave Sevilla the lead with a surging run through the Roma defence and a shot past keeper Pau Lopez in the 22nd minute.

Youssef En-Nesyri added the second just before halftime, tapping in a low cross from Lucas Ocampos.

Sevilla could easily have scored more, with two shots hitting the crossbar and a goal overturned for offside on video review.

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Playing after a packed run of Serie A games, Roma didn't muster a single shot on target in the first half and just one in the second.

"It was a great performance in all senses. We will enjoy it tonight, recharge our batteries and be ready for our next final in a few days' time," Reguilon said.

It was a single game at a neutral venue in Germany because no first leg was played in March before the season was suspended amid the coronavirus pandemic.

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No fans are allowed at any Europa League games.

It was Roma's first game since its $US700 million ($A968 million) takeover by the Texas-based Friedkin Group was confirmed on Thursday morning.

Sevilla next faces a quarter-final on Tuesday against Wolves after the English team squeezed past Olympiacos 1-0 on the night and 2-1 on aggregate for its first European quarter-final in 48 years.

Raul Jimenez scored the only goal from the penalty spot in the ninth minute after Olympiacos goalkeeper Bobby Allain gave away a spot-kick with a clumsy challenge after he failed to control the ball.

Both teams had plenty of chances to score in an action-packed second half but a combination of poor finishing and solid goalkeeping kept the score down.

Bayer Leverkusen earned a quarter-final against Inter Milan, beating Rangers 1-0 thanks to a powerful shot from Moussa Diaby for a 4-1 aggregate win.

Basel already had a 3-0 lead from the first leg and made the quarter-finals after Fabian Frei scored the only goal of the game in a 1-0 win over Eintracht Frankfurt.

Basel next plays Shakhtar Donetsk.

The teams in the final eight come from seven different countries, with only England having two - Wolves and Manchester United.

Source AAP