Colombian club Once Caldas claimed a memorable come-from-behind 2-1 victory against Brazilian giants Sao Paulo in their Group Two clash in the Copa Libertadores.
Sao Paulo went ahead after 33 minutes when former Brazil goalkeeper Rogerio Ceni came forward to fire home a free-kick.
The visitors maintained that advantage into the break, but four minutes after the re-start Fernando Uribe headed an equaliser for the Manizales-based side before man-of-the-match Dayro Moreno grabbed the winner 19 minutes from the end after dribbling past two defenders.
Once Caldas's win lifted them to the top of Group Two with a perfect record from their two games.
In Group Four, Argentinian side Lanus also recovered from a goal down before thumping Bolivian outfit Blooming 4-1.
Brazilian Luiz Vieira fired the hosts ahead early on with an outstanding shot from outside the box.
However, Lanus were ahead before half-time with playmaker Sebastian Blanco land Paraguayan Santiago Salcedo on target.
Lanus forward Diego Lagos then fired second-half double to clinch a first win for the Argentinians in three matches to keep their hopes alive.
Blooming remained pointless after three games.
In the other Group Four game, Peru's Universitario and Paraguayan outfit Libertad played out a goalless draw to stay level at the top with seven points.