Roma were held to a 2-2 home draw against Chievo after blowing a two-goal lead in Serie A.
The draw handed Roma a further setback ahead of their big clash with Real Madrid on Wednesday evening (Thursday morning AEST) in the UEFA Champions League.
Roma coach Eusebio Di Francesco had said in a press conference that the Chievo match was the most delicate of the next three games, and was key for his club to regain confidence after suffering a defeat and a draw in the past two Serie A matches.
Di Francesco did not rotate forward Edin Dzeko or defenders Aleksandar Kolarov and Kostas Manolas, but only granted a bit of rest to defender Federico Fazio and captain Daniele De Rossi, who played the last minutes of the match.
The game started well for Roma, who were up 2-0 at half-time thanks to forward Stephan El Shaarawy's goal 10 minutes into the match followed by midfielder Bryan Cristante 20 minutes later.
However, Roma showed down the pace in the second half, and their lack of aggressiveness allowed Chievo to narrow the gap just seven minutes after half-time with a goal from midfielder Valter Birsa.
The goal restored some of Chievo's confidence, leading to Mariusz Stepinski's equaliser with seven minutes to go.
Stepinski, 23, has proved himself capable against the big Italian clubs, as he has scored against defending champions Juventus and Inter Milan in his Serie A career.
Roma did their best in the final minutes to pull off a win, but Dzeko squandered a chance in the last minute.
Roma are seventh in Serie A with five points, while Chievo remain in last place table with a single point.