Lowry has returned home after playing 11 seasons in England, including stints at Aston Villa, Leeds United, Sheffield United, Millwall and most recently Birmingham City.
The 26 year-old has also appeared in two UEFA Europa League matches during his career.
"Shane is a quality defender and we know what he can do after he trained with us for several weeks in the pre-season last year," Glory coach Kenny Lowe said.
"He’s another WA boy who has come home. We hope he and Adam (Taggart) are two of many local boys who are keen to come home as part of our long term strategy."
After being away from his family for more than a decade in the United Kingdom, Lowry said it was time for a new adventure in his home town.
"I’ve really enjoyed my time in England and it’s been pivotal in shaping my football. The time was right to come to Perth and play with Glory, which has been a goal of mine in more recent years," Lowry said.
“As a Perth boy I’m keen to do my bit and steer the club to its first A-League championship, but more importantly help the team make the finals this current season."
Lowry, who represented the Republic of Ireland at Under-17 and Under-21 levels, opted to pursue a senior international career with Australia and was part of the 30-man preliminary squad for the 2010 FIFA World Cup.
The 26 year-old will join Glory for training on Thursday morning and will be available for selection for Saturday’s home match against Melbourne Victory at nib Stadium.
