AC Milan have opened their Serie A season with defeat at Udinese while Roma and Genoa shared six goals and Lazio won at Sampdoria.
New coach, more disappointment for AC Milan.
Rodrigo Becao scored his first professional goal to help Udinese beat AC Milan 1-0 as new Rossoneri coach Marco Giampaolo's first match in charge ended in defeat on Monday (AEST).
Giampaolo replaced Gennaro Gattuso in June and the former Sampdoria coach is already ready to give up his favoured 4-3-1-2 formation after a disappointing performance in which Milan didn't even have a shot on target.
"Certainly you'll see them in a different formation. I have to make them play in their natural roles," Giampaolo said.
"I saw things that weren't done well because of the characteristics of my players.
"Today's match gave me a lot to analyse and the three up front have to develop into a different attack."
Becao, who was signed by Udinese in the off-season, headed a corner into the bottom-right of the net in the 72nd minute.
Roma and Genoa also have new coaches in Paulo Fonseca and Aurelio Andreazzoli, respectively, and the two teams played out an entertaining 3-3 draw.
Hosts Roma will be the more disappointed of the two after leading three times thanks to goals from Cengiz Under and Edin Dzeko, and an Aleksandar Kolarov free-kick that hit the underside of the bar and dropped down just over the line.
However, Genoa fought back each time through Andrea Pinamonti, Domenico Criscito and Christian Kouame.
Luis Muriel scored twice as Atalanta fought back from two goals down to win 3-2 at SPAL.
Atalanta surpassed all expectations to finish third in the Serie A last season, qualifying for the UEFA Champions League for the first time in their history.
Ciro Immobile reached 100 Serie A goals and even added another as Lazio thumped Sampdoria 3-0 at the Marassi.
The well-travelled striker brought up his top-flight century with a lob before half-time and, after Joaquin Correa made it two, Immobile struck again on 62 minutes.
Simone Zaza scored twice against his former club Sassuolo as Torino won 2-1 at home.
Zaza headed Toro in front after 14 minutes and deflected Andrea Belotti's strike in for his brace midway through the second half.
Sassuolo's goal was tapped in by Francesco Caputo after Jeremie Boga's daisy cutter hit a post.
Serie B champions Brescia won 1-0 at Cagliari, with Alfredo Donnarumma scoring the only goal from the penalty spot.
Hellas Verona, another promoted side, drew 1-1 at home to Bologna despite playing most of the match with 10 men after Pawel Dawidowicz was sent off in the 13th minute for a dangerous tackle on Riccardo Orsolini.