Tromso effectively sealed its place in the second qualifying round of the UEFA Europa League with a 7-0 hammering of Tartu Santos.
The Norwegian side produced a superb performance in the first leg to all but secure progress, midifielder Magnus Andersen hitting a brace in a dominant win.
Rosenborg continued the theme of emphatic Norwegian success, Alexander Soderlund scoring twice, including one from the spot, in a 4-0 victory against Jelgava of Latvia.
Fellow Scandinavian side, and two-time competition winner, IFK Gothenburg will travel to Luxembourg under pressure next week after stumbling to a 0-0 draw with Fola Esch.
Botev Plovdiv was also a 4-0 winner over San Marino's Libertas, and Gilman Lika's injury-time strike gave Flamurtari Vlore a 3-2 triumph at Sioni.
Tiraspol's late comeback fell short as the Moldovan side lost 3-2 at home to Inter Baku, whose Azerbaijani rival Qabala faces an uphill battle in its away leg after a 2-0 reverse to Siroki Brijeg.
Slovenian side Koper took a commanding lead in its tie with 10-man Celik, Miroslav Covilo's double helping it to a 5-0 triumph.
There was treble joy for Kazakhstan, Astana winning 4-1 at Pyunik, Shakhter Karagandy beating Shirak 2-1 and Kairat earning a slender 1-0 success over Kukesi.
Metalurg Skopje was a 3-0 victor over Santa Coloma of Moldova, however, its Macedonian compatriot Turnovo was defeated 1-0 by Chikhura.
Scottish side Aberdeen is in control of its tie with Daugava Riga following a 5-0 home win in which the Latvian side was reduced to nine men.
It was a good night for Northern Irish sides as attacker Michael Carvill's 88th minute strike gave Linfield a 2-1 win at B36 in the Faroe Islands.
Crusaders backed up that result by beating Ekranas of Lithuania 3-1, and Derry City was a 4-0 winner in an all-British affair with Aberystwyth Town, which had goalkeeper Mike Lewis sent off after 23 minutes.
Airbus UK Broughton fared better in a 1-1 draw with Haugesund of Norway, however, Bangor City was thrashed 4-0 by Iceland's Stjarnan.
Finnish outfit VPS emerged as a 2-1 winner in all-Scandinavian clash with Brommapojkarna of Sweden, while its league rival MYPA beat IF of the Faroe Islands 1-0 thanks to Denis Abdulahi's strike.
But there was no such fortune for fellow Finnish side Honka, which lost 2-1 to Sillamae Kalev of Estonia.
Erik Sabo's brace proved key as Spartak Trnava won 4-2 at Hibernians.
Slovenian outfit Rudar drew 1-1 with Laci of Albania, but Andorra's Sant Julia has a mountain to climb if it is to qualify after losing 4-0 in Serbia to Cukaricki.
Mika is also in danger of going out following a 2-0 loss to RNK Split, but Nomme Kalju of Estonia travels back from Iceland with the advantage, overcoming Fram 1-0.
There was drama in another game in Iceland as FH scored three late goals, with two from Atli Gudnason, to beat Glenavon 3-0.
Vikingur was the only Faroe side to experience triumph, Andreas Olsen scoring the winner in a 2-1 defeat of Latvia's Daugava Daugavpils.
Meanwhile, Differdange, Vaduz, Buducnost and Diosgyor all claimed first-leg successes.
Elsewhere, there were goalless draws in the games between Veris and Litex Lovech, Banga and Sligo Rovers and Lovcen's trip to Zeljeznicar.