Kerr, who produced an incredible goal-laden campaign for both Perth Glory and the Chicago Red Stars in 2018-19, will face stiff competition from fellow nominees Pernille Harder, inaugural Ballon d'Or winner Ada Hegerberg, American Lindsey Horan and Japanese star Saki Kumagai.
Having lost out to England and Lyon defender Lucy Bronze last year, the 25-year-old will now have the chance to make amends when the winner is announced on May 22nd.
The Matildas captain claimed the W-League and NWSL Golden Boot awards last season and hit the ground running with a goal in Sunday's (AEST) opener against reigning U.S. Champions North Carolina Courage.
"The most rewarding thing for me (in the last 12 months) was back-to-back golden boots - in the NWSL and W-League," Kerr told BBC.
"I needed that season to prove to myself I could continually score. It's given me confidence going forward and it's my proudest moment."
While Kerr's consistency holds key to her hopes of victory, the 2018 Young Australian of the Year revealed it wouldn't be so without her teammates.
"It would be great to win this award so I can share it with my teammates. It's not all been about me," she said.
"Winning this award would be a nod to all the girls who have helped me in the team and given us success over the last year."