Iran was one of five nations to book a place at the 2015 Asian Cup with qualification victories.
The three-time winner of the tournament confirmed its progression from Group B with a 4-1 win over Lebanon in Beirut.
Oman, Uzbekistan, Qatar and Kuwait progressed courtesy of respective wins over Syria, Hong Kong, Malaysia and Thailand.
Iran was given a first-half lead by Esteghlal defender Amir Sadeghi, and three further goals came the visitor's way prior to Mohamed Haidar's consolation.
Lebanon's defeat - combined with Kuwait's 3-1 win over Thailand - leaves Giuseppe Giannini's side battling for the best third-place finish and means Kuwait has reached its 10th Asian Cup as runner-up behind Iran.
Oman booked a third appearance in the tournament thanks to a 91st-minute strike from Eid Mohammed against Syria, while Abdulkarim Salem was Qatar's match-winner with a 65th-minute strike against Malaysia in Shah Alam.
Goals in the final six minutes from Vokhid Shodiev and Odil Akhmedov were enough to see Uzbekistan beat Hong Kong 2-0 and confirm a sixth appearance at the final tournament.
Three sides who had already ensured qualification remain top of their respective groups after maintaining their unbeaten runs.
United Arab Emirates produced a dominant performance in Abu Dhabi, beating hapless Vietnam 5-0.
The Group E leader was four goals ahead by half-time, with the top-scorer in qualification - Ali Ahmed Mabkhout - netting the third after half-an-hour.
A goal in the opening minute from Mohamed Salmeen put Bahrain in control against Yemen, and Faouzi Aaish added a second with two minutes remaining to secure a 2-0 win and guarantee his side kept top spot in Group D ahead of Qatar.
Saudi Arabia - which has already won Group C - dropped points for the first time in qualification as China held it to a goalless draw in Xi'an, while Iraq kept its hopes of usurping China alive with a 2-0 win over Indonesia.