Germany have confirmed midfielder Julian Draxler will not join their squad for the UEFA Nations League game against Netherlands.
Draxler had been included by coach Joachim Low but missed their friendly win over Russia as he was granted compassionate leave.
Germany's relegation from League A was confirmed when the Netherlands won 2-0 at home against world champions France.
And Germany have now announced Draxler will not join the rest of the squad for Monday evening's (Tuesday morning AEDT) match against Ronald Koeman's men in Gelsenkirchen.
Nations League relegation rounds off an atrocious year for Low's Germany, who flopped badly in Russia with a dire 2018 FIFA World Cup title defence.
Germany exited the tournament in the group stage having finished bottom of a section that included Sweden, Mexico and Korea Republic.
However, Low has been boosted by Marco Reus returning to training with the team on Saturday, the playmaker having sat out the 3-0 defeat of Russia.
Borussia Dortmund captain Reus has been in inspirational form to help his team go top of the Bundesliga, scoring eight goals including a double in a 3-2 Der Klassiker win at home to title rivals Bayern Munich last time out.