Socceroos defender Milos Degenek was among the scorers as his Red Star Belgrade side clinched their third successive and a record-extending 31st Serbian league title with a 5-0 win at city rivals Rad.
Celebrations were muted, however, as the game was played behind closed doors on the league's resumption after the enforced Covid-19 pandemic break.
Second-bottom Rad were on the back foot throughout and fell behind in the 24th minute when Mirko Ivanic converted a penalty after Aleksa Vukanovic was fouled just inside the area.
Centre-back Srdjan Babic doubled Red Star's lead in the 30th from close range and Vukanovic added the third six minutes later with a crisp shot into the far corner from 10 metres.
Australia defender Degenek then headed in the fourth goal from an El Fardou Ben Nabouhane corner in the 57th minute before the lively Vukanovic tapped in Ivanic's fizzing low cross in the closing stages.
With three rounds of matches remaining, Red Star have 72 points from 27 games, 14 more than closest rivals Partizan Belgrade who are at home to Mladost Lucani on Sunday (AEST).
Up to 1,000 fans will be allowed to attend games as of next weekend when Red Star are at home to Radnik Surdulica, with the Serbian government continuing to ease lockdown measures.
Red Star's head coach Dejan Stankovic, said: "All credit goes to the players, the staff and the fans, who put wind in our sails every step of the way. We'll have some champagne tonight, we've earned it."