Serie A's bottom club Crotone recorded their first win of the season with an emphatic 4-1 victory at home to Spezia.
Elsewhere on Saturday, Hellas Verona won 2-1 at Lazio, leapfrogging the Romans to occupy sixth place, while Udinese beat Torino 3-2 to clinch a third straight win and leave their Turin hosts in the relegation zone.
Crotone went into the game between the two promoted sides as the only team in the Italian league yet to win, having picked up just two points all season.
They hadn't even scored in their last four matches but Junior Messias broke the goal drought in the seventh minute following a rapid counterattack.
A mistake by Crotone midfielder Niccolo Zanellato led to Diego Farias equalising 11 minutes later for the visitors.
Crotone, who remain bottom, started the second half aggressively and Arkadiusz Reca and Eduardo Henrique both netted shortly after the interval before Brazilian Messias netted his second in stoppage time.
At the Stadio Olimpico, Manuel Lazzari scored an own-goal and Lazio gifted Adrien Tameze the winner after Felipe Caicedo had equalised for the hosts early in the second half.
Lazio were riding a wave of enthusiasm after reaching the knockout stage of the Champions League for the first time in 20 years.
But Verona's first victory over the Biancocelesti since 2013 saw them leapfrog two points above Lazio into sixth spot.
In Turin, Argentine Ignacio Pussetto finished off a counter-attack in the first half and his compatriot Rodrigo De Paul drilled in a clinical shot for the visitors' two-goal lead.
Home captain Andrea Belotti and substitute Federico Bonazzoli levelled by the 67th minute, only to see Ilija Nestorovski, himself a substitute, net the winner two minutes later.
The Italian international Belotti netted his eighth goal this season, and the 100th since joining 'Il Toro' in 2015.