Coton Sport will be out for revenge when it plays Al Ahly in the first leg of its CAF Confederation Cup semi-final on the weekend.
In October last year the Egyptian giant beat the Cameroonians on penalties in the semi-finals of the continent's premier club competition, the CAF Champions League.
Vengeance will not be easy, though. Al Ahly will be filled with confidence after it beat arch-rival Zamalek on penalties to claim its eighth Egypt Super Cup on Sunday (Monday AEST).
The Cairo giant will also be keen to add to its 19 international club trophies, which has seen it being officially recognised by CAF this year as the most decorated club in the world.
With both AC Milan and Boca Juniors on 18 international club trophies, the addition of the CAF Confederations Cup this year should be enough to keep it on top for at least another season.
Coton Sport will be confident in its own right. It tops the Cameroon Elite One league having won its last five matches in a row and also qualified for the Cameroon Cup finals after beating Etoa Meki last week.
In the other semi-final first leg, Sewe Sport welcomes the Democratic Republic of Congo's AC Leopards to the Stade Municipal in San-Pedro having never made this stage of a CAF competition before.
That didn't stop club chairman Eugene Diomande declaring: "Our ambition is to qualify for the final and win it."
He has the right to be bullish about his team's prospects as it has not lost at home in its past six matches and will still be buoyed by its superb 3-0 win over Nkana to secure its place in the final four.
AC Leopards will be no pushover, though. It knows what it takes to go all the way having already etched its name onto the Confederation Cup trophy when it won it in 2012 after beating Djoliba AC 4-3 on aggregate.
The Congolese side has a habit of scoring four goals when it needs to in this competition, after it beat ASEC Mimosas of Ivory Coast 4-1 to qualify for the semis and in the matchday five beat the other semi-finalist Coton Sport 4-0.
The Confederation Cup semi-final first legs between Coton Sport and Al Ahly, and Sewe Sport against AC Leopards both take place on Saturday (Sunday AEST) with the return legs due on September 27.