Chile's Colo Colo traveled on Monday to Brazil, where it will face Palmeiras this week in the second leg of the Copa Libertadores quarterfinals series.
The Chilean club, which was beaten by Palmeiras 2-0 in the first leg of the series, will be without Esteban Paredes, one of its top scorers, in Wednesday's match.
Colo Colo is heading into the match after being beaten by Chilean league leader Universidad Catolica on Sunday.
Paredes was injured in the match and underwent an MRI a few hours later.
The 38-year-old forward will be out 10-14 days with a left thigh injury.
Colo Colo will also have to take the field without Argentine winger Damian Perez, who was tossed out of the first-leg match.
Colo Colo manager Hector Tapia, however, told reporters at the Santiago airport that his squad was not ready to throw in the towel.
"We're not closing the door on the Palmeiras" match, Tapia said, adding that "everything is still very raw after the match with Catolica and what happened afterwards, like the injury to Esteban (Paredes)."
The manager added winger Gonzalo Fierro and midfielder Jaime "Pajarito" Valdes, who were not in the lineup against Universidad Catolica, to the roster for the Palmeiras match.
"You have to get over losses, you have to shake them off," Tapia said.
SBS will be broadcasting a game from the Copa de Libertadores, River Plate vs Independiente will be LIVE, FREE and in HD on SBS from 8.15am (AEST) on Wednesday October 3.