Coach Jose Saturnino Cardozo was sacked by Mexican football club Chiapas for the second time in a week after Sunday's (AEST) 3-0 home defeat by Cruz Azul.
The Paraguayan, who has presided over seven defeats in nine matches of the Apertura championship, had been first sacked on Tuesday (AEST) before being reinstated the next day as a result of player pressure.
"The board of directors and Jose Saturnino Cardozo decided by mutual accord to end their working relationship," Chiapas said in a statement.
"The team thanks the Paraguayan tactician for his professionalism, commitment and dedication."
Chiapas, who are bottom of the league standings with four points, had hoped the events earlier in the week would motivate the team to do better.
"We needed something like this for the players to realise what a bad situation we're in," club president Carlos Lopez Chargoy said.
Sergio Bueno was named as Cardozo's replacement for his third spell at the club where he has previously worked in 2003 and from 2013-2015.
He will take charge for Thursday's (AEST) match against Leon.