Chelsea will host Manchester United in the standout tie of the Capital One Cup fourth-round draw.
United will travel to
The Blues hammered Wolverhampton Wanderers 6-0 in the last round.
Holder Liverpool will welcome Swansea City to Anfield in a match which will see Reds boss
Liverpool came from behind to see off West Bromwich Albion, while the Swans scraped past Crawley Town.
Manchester City's conqueror Aston Villa was rewarded for knocking out the Premier League champion with a trip to Swindon Town.
Arsenal, a 6-1 winner over Coventry City, will travel to Reading, while north London rival Tottenham Hotspur also progressed and is now set for a meeting with Norwich City at Carrow Road.
Leeds United, which ended Everton's hopes, will be at home to Southampton.
There will be a north-east derby at the Stadium of Light as Sunderland takes on Middlesbrough - the teams met in the FA Cup last season.
Wigan Athletic will host the lowest-ranked side left in the competition, League Two outfit Bradford City.
The ties will be played in the week commencing 29 October.
Capital One Cup fourth-round draw
Sunderland v Middlesbrough
Swindon Town v Aston Villa
Wigan Athletic v Bradford City
Leeds United v Southampton
Norwich City v Tottenham Hotspur
Liverpool v Swansea City
Chelsea v Manchester United
Reading v Arsenal