Inter Milan will make its Europa League debut with a home leg first against Hajduk Split of Croatia or Skonto of Latvia in the third qualifying round.
Inter dropped into UEFA's second-tier competition this season after seven straight years in the UEFA Champions League, which it won in 2010.
Liverpool, the 2005 Champions League winner, also featured in Friday's draw, and will travel first to face Renova of Macedonia or Gomel of Belarus.
Athletic Bilbao, runner-up last season, is at home first against Croatia's Slaven Koprivnica or Northern Ireland's Portadown.
Marseille is away first against Eskisehirspor of Turkey or St Johnstone of Scotland.
First-leg matches are played on August 2. Return matches are on August 9.
Winners advance to a playoff round before the group stage.
UEFA Europa League
Malaga has been able to reduce its suspension from competing in European competitions to one year.