Real Betis defender
Roque, who came through the youth ranks at Liverpool before returning to his homeland with Betis, underwent surgery to remove a tumour in his pelvis last year.
A statement on Betis' official website read: "The Real Betis player
"Real Betis send their deepest condolences to the Roque family."
Roque spent four years at Liverpool between 2005 and 2009 and helped the club win the 2006 FA Youth Cup. He made one substitute appearance for the first team, against Galatasaray in a UEFA Champions League match in
While at Anfield Roque had loan spells with Oldham Athletic and Spanish sides Xerez and Cartagena before moving permanently to Betis in 2009, making his senior debut with the Spanish club in
A Liverpool statement read: "