Racing Santander became the first casualty of the Primera Division season as it bid farewell to its top-flight status after losing 3-0 at Real Sociedad.
Highly-rated French winger Antoine Griezmann netted twice in the second half before setting up Imanol Agirretxe for Sociedad's third seven minutes from time as Racing's 10-year spell in La Liga came to end.
The writing has been on the wall for some time for Racing, which has taken just three points from the last 13 games and is without a victory since mid-January.
Third-bottom Sporting Gijon look determined to avoid the same fate as Racing and it gave its hopes of survival another big boost with a 3-0 win at Espanyol.
Second-half goals from
Villarreal looked set to move six points clear of the drop zone after taking a 44th-minute lead through
That was a blow for Villarreal but it received good news from elsewhere as 16th-placed Granada lost 3-1 at UEFA Champions League-chasing Levante.
Levante moved back into the top four ahead of Malaga, who play third-placed Valencia on Monday (AEST), thanks to goals from
In the other match, Real Mallorca leapfrogged Getafe into the top 10 with a three-point haul at the Coliseum Alfonso Perez.
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