European champion Bayern Munich kicks off the new Bundesliga season at home to Borussia Moenchengladbach, which is looking to ruin Pep Guardiola's German league debut.
Ex-Barcelona boss Guardiola took over in June and inherits the side which became the first German team to win the treble of European, league and cup titles last season.
Bayern was beaten 1-0 in Munich by Moenchengladbach in its opening game of the season two years ago when Igor de Camargo's second-half header shocked the host.
Much has changed since then with Bayern having assembled a powerful squad. Guardiola has the pick of 10 full internationals in his midfield, including Spain Under-21 captain Thiago Alcantara, a new arrival from Barcelona.
But the expectations of delivering the instant success Bayern is used to is weighing on Guardiola.
"It's not easy having to always win," said the Spaniard, who has had eight weeks to work with his team.
"People expect us to win by six or seven nil, and that's just not possible."
Gladbach has made three signings since last season with Germany striker Max Kruse joining from Freiburg, Brazil's Raffael from Dynamo Kiev and Germany Under-20 midfielder Christoph Kramer brought in on loan from Leverkusen.
The chance to shake up the league by claiming Bayern's scalp is firing up the underdog, according to Moenchengladbach's right-back Tony Jantschke.
"The game will be broadcast in more than a hundred countries, the eyes of the world will be watching us," said the defender, who will be marking Bayern's attacking star, Franck Ribery.
"There is nothing better for a footballer, even if you know that a difficult game awaits us in Munich and we're the underdogs.
"Games against Bayern have always been close over the last few years and hopefully, with a bit of luck, we can take a few points home."Borussia Dortmund opens its season at Bavaria's Augsburg with new-signing Henrikh Mkhitaryan unlikely to start after tearing ankle ligaments in pre-season.
Dortmund's other new signings, Pierre-Emerick Aubameyang and Greece defender Sokratis Papastathopoulos, will feature while Augsburg's Turkey forward Halil Altintop makes his return to the Bundesliga from Turkish side Trabzonspor.
There will be a interesting opener at Bayer Leverkusen with Sami Hyypia's team hosting Freiburg, which just missed out on a UEFA Champions League place, but has lost five first-team regulars since last season.
Leverkusen has recruited heavily in the off season by signing South Korea striker Heung Min Son from Hamburg and Australia winger Robbie Kruse from Fortuna Duesseldorf while Italy Giulio Donati and Germany's Roberto Hilbert strengthen the defence.
Bayer impressed in the pre-season with a 4-0 win over Vitesse Arnhem and a 6-1 hammering of minnow Lippstadt in the Germany Cup.
Freiburg has several new arrivals with 22 year-old French midfielder Francis Coquelin quick to impress since signing on loan from Arsenal, while Sporting Lisbon's Gelson Fernandes adds midfield depth and his Swiss compatriot Admir Mehmedi, another loan arrival from Dynamo Kiev, brings further promise of fresh punch to the frontline.
Having won promotion from the second division, Eintracht Braunschweig hosts Werder Bremen, while Hertha Berlin hosts Eintracht Frankfurt in the capital.
Central Coast Mariners has been eliminated from the AFC Champions League after a 1-0 loss to Sanfrecce Hiroshima in Japan.