The midfielder played his first match for more than a year in the Under-21s at West Bromwich Albion on Monday afternoon (local time) having been sidelined by a niggling ankle problem and then knee surgery.
Wilshere, 20, is set for another run-out next week against Reading, but Wenger continues to stress it must be a cautious rehabilitation for the 20-year-old.
"Jack needs a few games, progressive build-up to get his body used again to competition, to shocks, to fights, but he is doing extremely well, the situation looks very good," said Wenger, whose side will look to get its Premier League campaign back on track at West Ham United this weeked after defeat by leader Chelsea.
"We have to be cautious, not crazy, because of his talent you are always pushed in a situation where you would like to rush him back, and we have to resist that.
"The next match should be next week and he is working very hard.
"The body is like that, when you have been out of competition for 14 months it takes a long time to find your sharpness back. You cannot rush it."
Wenger hopes a steady fitness programme will see long-term benefits for everyone.
"There are three things that are important for every player: the health of the player, the interests of the club and the interests of the national team," said Wenger.
"You have to try to combine the three but the most important thing of course is the health of the player.
"[England manager]
Hodgson called up left-back
Right-back
"Yes [it is a change] because I faced many times of course some questions about that," said Wenger.
"I always said that the ideal mixture was to have a basic young squad where 60 per cent comes from this country and 40 per cent maybe from abroad. We get slowly there and we have good young talent from England."
Arsenal heads to
Wenger expects another stern test against the Irons.
"They have a good balance, they are efficient, they are a good mixture I must say between direct play and playing on the ground," he said.
"Technically they are quite sound in midfield, they have Carroll and
"We know we will have a big challenge there, we know we will only get away with the points if we perform at our best."
Murdocca trades in Roar for Heart
Long-serving Brisbane Roar midfielder Massimo Murdocca has been granted a release to return to his family in the Victorian capital and link up with Melbourne Heart.
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