Tottenham Hotspur will head into its second UEFA Europa League group match away to Panathinaikos brimming with confidence after notching up a rare Premier League victory over Manchester United on the weekend.
After a slow start to Andre Villas-Boas' reign at White Hart Lane, three straight league wins including the 3-2 thriller at Old Trafford have taken Spurs into fifth place and seem to have turned the tide for the Portuguese manager.
A first win over Sir Alex Ferguson's team since May 2001 left Villas-Boas declaring: 'We don't stop here' as Tottenham aims for a first European trophy since 1984 when it beat Anderlecht to claim the then-UEFA Cup.
"We feel confident now and our form has been impressive," said the former Chelsea boss, who won the Europa League with Porto in 2011.
"We don't stop here though. We have to improve our home form as well and we have to focus on that to make sure we continue this sequence.
"We now go to Panathinaikos and we are missing one match to complete the series (of away matches at Carlisle, Manchester United and Panathinaikos). It will be important to get the win there to put us back on track in the group stage of the Europa League."
Tottenham was held to a 0-0 draw by Lazio in its opening Group J match, and the Italian side now hosts Slovenian club Maribor.
Lazio chiefs will be hoping to avoid a repeat of the racist chanting directed at three of Tottenham's black players, Jermain Defoe, Aaron Lennon and Andros Townsend, and which is being investigated by European football's governing body UEFA.
Tottenham's Premier League rival Liverpool almost paid the price for fielding a near second-string side for its Europa League opener with Swiss side Young Boys, but held on to win a thrilling match 5-3.
"Of course we could have defended better and there is no question the three goals we gave away were disappointing," said Liverpool manager Brendan Rodgers, who has come under pressure with his team having racked up just one win in its six league outings this season.
"But to draw positives, the young players were so courageous and brave to play and show that confidence, and my senior players were very much together and kept the young guys going."
The third Premier League club in action is Newcastle United, which hosts high-flying Ligue 1 side Bordeaux, which comes into the match on the back of a 2-0 away win over Lyon.
Like Spurs, Newcastle was held to a 0-0 draw, by Maritimo on the island of Madeira, and will be hoping to close down a Bordeaux attack that notched up four goals in its opener against Club Brugge.
In Group H action, Italian giant Inter Milan travels to Azerbaijan to play Neftci PFK, which proved its worth by eking out a goalless draw away to Partizan Belgrade.
Inter needed an injury-time goal from Japan defender Yuto Nagatomo to claim a 2-2 draw against Rubin Kazan.
Defending champion Atletico Madrid hosts Czech club Viktoria Plzen, having comfortably beaten Israeli club Hapoel Tel-Aviv 3-0 in its opener.
Atletico, a 3-0 victor over La Liga rival Athletic Bilbao in last season's final, demolished Chelsea 4-1 in the UEFA Super Cup and will be looking to extend its European winning streak to 15 matches in the Group B clash.
The trial of Franck Ribery and Karim Benzema for having sex with an under-age prostitute opened on Tuesday but was immediately suspended pending resolution of a point of law which may result in charges against the footballers being dropped.