Freiburg moved a step closer to European qualification as it beat Augsburg 2-0 while Hamburg could only manage a draw against Wolfsburg.
Augsburg remains in the bottom three with two games remaining.
Hamburg fell three points behind Freiburg in the race for the top six as it was held to a 1-1 draw against Wolfsburg.
Bayer Leverkusen pushed Nurnberg closer to relegation to the 2. Bundesliga and returned to the top four with a convincing 4-1 win in Bavaria.