Northampton knocks out Cardiff

Heidar Helguson gave the Bluebirds a dream start by converting a second-minute penalty but David Artell equalised for the Cobblers on 37 and Alex Nicholls sealed a shock win by heading home just after the restart.

Gus Poyet's Brighton & Hove Albion was also on the end of a shock defeat as it went down 3-0 to Paolo Di Canio's newly-promoted League One Swindon Town at the County Ground.

Paul Benson put Di Canio's men in front in the 53rd minute and a late brace from Alan Navarro sealed a fantastic victory.

Bristol City was the third Championship side to crash out as it was beaten 2-1 by Gillingham at Ashton Gate.

Danny Kedwell's penalty just before the break put the Gills in front and Ben Strevens looked to have sealed victory with a 54th-minute strike. City substitute Marvin Elliott scored a consolation goal in injury-time.

Birmingham City survived an early scare against League Two Barnet at St Andrew's when Jon Nurse put the visitor in front in the 31st minute.

The Blues blazed back with a Marlon King penalty on 38 and further goals from Stephen Caldwell and Darren Ambrose, before injury-time strikes from Wade Elliott and Peter Lovenkrands made the final scoreline harsh on the London side.

Crystal Palace was also forced to come from behind to beat Exeter City 2-1 at St James Park.

John O'Flynn put the host ahead early on, but Jermaine Easter's penalty and a Kagisho Dikgacoi goal before half-time won it for the Eagles.

League Two Bristol Rovers took a surprise 26th-minute lead at Ipswich Town through Michael Smith, but the Tractor Boys turned it round with Jason Scotland, Tommy Smith and Aaron Cresswell setting up a 3-1 win.

Burnley was yet another Championship side forced to come from behind as Chris McCann, Charlie Austin and Dean Marney cancelled out an early Chris Shuker effort in a 3-1 win at Port Vale.

There were no such problems for Leicester City, which won 4-0 at Torquay United with goals from Lloyd Dyer, Ben Marshall, Matthew James and Jamie Vardy, or Peterborough United, which beat Southend United at London Road by the same score.

Crisis club Portsmouth crashed 3-0 at Plymouth Argyle, while another newly-relegated side, Coventry City, squeaked past League Two Dagenham & Redbridge with Kevin Kilbane's injury-time penalty.

League One Stevenage beat AFC Wimbledon 3-1 and Yeovil Town won an all-League One clash 3-0 at home to Colchester United.

League One Scunthorpe United staged a stupendous comeback to knock out Championship Derby County 7-6 on penalties at Pride Park after a 5-5 draw in normal time.

Nigel Clough's Rams led 3-0 and 5-3 before the Iron forced an extra half-hour by scoring twice in injury-time through a Connor Jennings strike and Bobby Grant's last-gasp penalty.

Newly-promoted Charlton Athletic was another Championship side to fall as it went down 4-3 on penalties to League One Leyton Orient at The Valley.

Scott Wagstaff gave Charlton a 28th-minute lead but Mathieu Baudry equalised in first-half injury-time and the visitor held its nerve to win 4-3 in the shootout with Ryan Brunt firing home the decisive kick.

And Millwall also missed out on penalties to League One Crawley Town at the New Den.

Hope Akpan and Nicky Adams twice put the visitor ahead only for the Lions to haul their way back through Darren Ward and Shaun Batt respectively.

But the visitor eased through the eventual shootout 4-1 with Crawley goalkeeper Paul Jones the hero as he saved from Darius Henderson and Jack Smith.

Abdulai Bell-Baggie scored in the last minute of extra-time to give Tranmere Rovers a 2-1 win at Chesterfield, while League Two Oxford United pulled off a minor upset with a 5-3 penalty win over AFC Bournemouth after a goalless draw.