With more than 58 million mentions on Twitter in 2015, the 28 year-old is also one of the most popular and recognised people on the planet.
Here are some of the best reaction to Messi's latest gong and the 2015 Ballon d'Or awards ceremony.
Shoutout to those who keep it from being just another dull awards night
The best (most likely fake) quote of the night goes to
Ronaldo didn't seem to enjoy it too much
It was all about this man
Leo Messi - the 2015 FIFA Ballon D’Or winner. 61 matches, 52 goals, 26 assists and 5 trophies. Here's just some of those magic moments. Posted by SBS The World Game on Monday, 11 January 2016