It will be the first time the Matildas go head-to-head with USA since their 3-1 defeat at the opening group stage match of the FIFA Women's World Cup Canada 2015 and their first game since a 1-0 defeat to Japan in the quarter-finals.
Matildas head coach Alen Stajcic said the matches would hone his players' skills and they couldn't have asked for better preparation ahead of the 2016 Rio Olympics.
"Our goal is to keep improving on our consistency, on our maturity on the ball, there are still a lot of areas we need to improve on," he said.
A handful of Matildas are currently playing in the USA's National Women's Soccer League and Stajcic says he can already see their improvement.
"They're showing it wasn't a fluke that we performed well on the world stage and I know that they're going to bring this experience back into the national team," he said.
"The more players we have playing overseas the more experience they're getting and the better it is for our national team."
The matches will take place on 18 and 21 September (AEST) in Detroit and Birmingham respectively.