Glory's new-look squad showcased its potential on Sunday with a 1-1 draw against Spanish La Liga side Malaga at nib Stadium.
Malaga went ahead through Ricardo Horta in the 32nd minute, but Glory got a deserved equaliser when Republic of Ireland international Andy Keogh scored on the turn in the 57th minute.
Keogh wasn't the only new Glory recruit to shine, with former Western Sydney Wanderers winger Youssouf Hersi, Richard Garcia, Diogo Ferreira, Mitch Nichols and Dino Djulbic also performing strongly.
Glory's FFA Cup campaign kicks off with a tough round-of-32 encounter against fellow A-League outfit Newcastle Jets on 5 August.
Lowe is keen to win the nationwide tournament rather than merely use it to experiment.
"We want to win it. You want to go as far as you can," Lowe said.
Former Newcastle Jets skipper Ruben Zadkovich is nursing a knee complaint and won't be able to feature against his old side on Tuesday week.
Glory midfielder Rostyn Griffiths will also be absent with his own knee issue.
"He has had an injection in his knee - he had some blood re-injected, so that's a six-weeker," Lowe said of Griffiths.
"It's a growth thing, not an injury."
Glory will also be without Hersi, who has been selected for the A-League All Stars match against Juventus on 10 August.
Perth only narrowly avoided the wooden spoon last season, with the dire on-field results matched by issues off the field.
However, a positive vibe has swept through the club during the off-season, with the swell of quality signings boosting confidence of a successful season.
"There's a lot of optimism at the club," Lowe said.
"The players are buying in and setting their own standards, and trying to raise the bar themselves without a lot of real drive from the coaching staff.
"I think we look fitter, brighter, and everyone seems to be together and there is a good vibe about the place."