The two-day tournament, on 18 and 19 May, will mark the beginning of the first phase of the Jets’ pre-season training schedule.
A 10-man squad will make the trip for the six-a-side competition - with the club's reigning Player of the Year Mark Birighitti and club captain Ruben Zadkovich among those considered for the travelling party.
'Asia is one of the world’s fastest growing football markets," CEO Robbie Middleby said.
'This is a great opportunity for us as a Club to build the Newcastle Jets brand and promote the A-League in Singapore and throughout Asia in general.
'Taking part in an event like this is a great way to get our preparations for the next A-League season started.
'Any overseas trip gives the players involved the chance to build camaraderie and cohesion within the squad.
'I’m sure coming up against some quality international opposition will be an extremely beneficial experience for our players, especially for some of the younger ones."
The tournament will be hosted by the Singapore Cricket Club (SCC) on the hallowed Padang, set in the shadows of Singapore’s finest colonial buildings and incidentally within the perimeter of Singapore’s celebrated F1 circuit.
Other teams in the tournament include Chonburi FC (Thailand), Singapore U23's, Hong Kong FC (China) and Geylang International (Singapore).
Click here to find out more about the Soccer Sixes tournament in Singapore.