Cruz Azul and Union Espanola each recorded their second win in the Copa Libertadores group stage when they saw off Venezuelan opposition.
Mexican side Cruz Azul hammered Deportivo Tachira 4-0 while Chilean side Union enjoyed a 3-1 success against Bolivar in Venezuela.
Adrian Cortes' 18th-minute penalty set Cruz Azul on its way to victory in Group Six.
Edixon Perea made the game safe (54) before Javier Orozco Penuelas and Emanuel Villa gave the scoreline a more emphatic look.
In Group Three, Bolivar took a first-minute lead against Union through Edemir Rodriguez but was pegged back by two goals in five minutes from Mauro Diaz (62) and Emanuel Herrera (66). Substitute Jean Paul Pineda scored a late third for the visitor.
Arsenal Sarandi bounced back from the opening Group Four loss to Fluminense by beating Zamora, ensuring a hat-trick of Venezuelan defeats.
The result was barely in doubt once Jorge Ortiz and Carlos Carbonero had scored in the opening quarter-hour and Luciano Leguizamon rounded off the scoring before half-time.