Uzbekistan champion Bunyodkor won 1-0 at Seongnam Ilhwa Chunma - winner of the Asian Champions League in 2010 - to book its spot in the quarter-finals.
Defender Hayrulla Karimov's penalty seven minutes after the interval, after an infringement by Lim Jong-Eun in the area, condemned the South Korea outfit to a narrow defeat.
Jon McKain helped Adelaide United into the quarter-finals after his strike gave it a 1-0 win over Nagoya Grampus at Hindmarsh Stadium.
The former captain's close-range finish in the 40th minute was enough to see off the Japanese outfit as United advanced to the last eight.
AFC Champions League
Patrick Zwaanswijk will rely on his vast experience to help him
keep the emotion out of it when he plays his last game for Central
Coast Mariners against Guangzhou Evergrande on Wednesday.